Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. Keywords: E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins. Cell-permeable, ethyl ester of Ec. The ester is hydrolyzed by intracellular esterases to produce Ec. Inhibits calpain and cathepsins B, H, and L. Inhibits . Membrane-Permeant Cysteine Protease Inhibitor E64d. S. Eksi,1 B. Czesny,1 G.- J. . or without protease inhibitors, M E64d (Sigma, St Louis, MO), 10 M.

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E-64-d (CAS 88321-09-9)

Tokyo 35, Abstract. Ed, sc, is a white solid. Our New Product guide highlights over new products added in the second half of Santa Cruz Biotechnology, Inc. Autophagy 1 84 PMID: Journal of immunology Baltimore, Md.

The compound can permeate an intact cell and block the activity of calpain, which results in the protection of protein kinase C PKC from proteolysis.


Kim et al Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Ed is also a cathepsin B, cathepsin H, and cathepsin L inhibitor. Tocris products are intended for laboratory research use only, unless stated otherwise. Concentration 1 femtomolar picomolar nanomolar micromolar millimolar molar. Citations 1 to 6 of 6 total Display: Add to order list. Cell culture, Abstract. Email address already exists, please enter a new valid email address.

Inhibitor of cathepsins B and L; also thought to inhibit calpain. What is the appearance of the compound? Volume nanoliter microliter milliliter liter.

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E 64d Supplier | CAS | E64d | Tocris Bioscience

The Journal of biological chemistry. Published data Date published: For Research Use Only.

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ED Calpain and cathepsin inhibitor.

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